About Costello Syndrome

Costello Syndrome, also known as faciocutaneoskeletal syndrome, is related to cardiofaciocutaneous syndrome 1 and noonan syndrome with multiple lentigines, and has symptoms including hoarseness and koilonychia. An important gene associated with Costello Syndrome is HRAS (HRas Proto-Oncogene, GTPase), and among its related pathways/superpathways are Apoptotic Pathways in Synovial Fibroblasts and ERK Signaling. The drug Anesthetics has been mentioned in the context of this disorder. Affiliated tissues include skin, heart and brain, and related phenotypes are macrocephaly and short neck

Major Symptoms of Costello Syndrome

Costello syndrome is a rare autoimmune disorder that primarily affects the liver and kidneys. It is characterized by symptoms such as jaundice, itching, and swelling in the face and neck. The exact cause of Costello syndrome is not known, but it is thought to be related to an abnormal immune response to a protein called GQMB. Treatment typically involves medications to manage symptoms and prevent complications, such as biologics and supportive care.

Suitable Lifestyle for People with Costello Syndrome

Costello syndrome is a rare genetic disorder that causes the skin on the face and body to become thin, bruise easily, and become susceptible to infection. Patients should adopt the following lifestyle:

1. Avoid strenuous exercise to avoid bruises after injury;

2. Pay attention to diet and eat more foods rich in vitamin C and E, such as fruits, vegetables and nuts;

3. Pay attention to skin care and apply Use sunscreen to protect your skin and avoid prolonged exposure to the sun;

4. Seek medical treatment regularly and receive treatment according to the doctor's recommendations;

5. Maintain a good attitude and avoid excessive mental stress.

Other Diseases

Cat Eye SyndromeNDH SyndromeKBG SyndromeICF SyndromeH SyndromeFG Syndrome3C Syndrome3-M SyndromeDown SyndromeCushing SyndromeBarakat SyndromeIMAGe SyndromePeters-plus SyndromeRotor SyndromeVici SyndromeRoberts SyndromeUrofacial SyndromeBasan SyndromeBartter SyndromeCurrarino Syndrome