About Renal Tubular Dysgenesis

Renal Tubular Dysgenesis, also known as primitive renal tubule syndrome, is related to oligohydramnios and anuria. An important gene associated with Renal Tubular Dysgenesis is REN (Renin), and among its related pathways/superpathways are p70S6K Signaling and Peptide hormone metabolism. Affiliated tissues include kidney, lung and bone, and related phenotypes are hypertelorism and polyhydramnios

Major Symptoms of Renal Tubular Dysgenesis

Renal tubular dysgenesis, also known as congenital renal tubular acidosis, its main symptoms include:

1. Oliguria: Due to abnormal renal tubular function, the renal tubular ability to absorb water and electrolytes in the original urine decreases, resulting in urine output reduce.

2. Increased nocturia: Patients will feel the need to urinate frequently at night and need to go to the toilet frequently, resulting in decreased sleep quality.

3. Hematuria: Due to the increased destruction of red blood cells by the renal tubules, the blood cells filtered by the glomerulus enter the urine, causing hematuria.

4. Cast urine: A large number of casts appear in the renal tubules, causing the appearance of urine to change.

5. Hypokalemia: Due to reduced reabsorption of potassium by the renal tubules, blood potassium levels decrease.

6. Hyperphosphatemia: Increased blood phosphorus levels due to reduced renal tubular reabsorption of phosphorus.

7. Hypocalcemia: Due to reduced reabsorption of calcium by the renal tubules, blood calcium levels decrease.

8. Renal tubular acidosis: due to reduced reabsorption of hydrogen ions and bicarbonate ions by the renal tubules, resulting in an imbalance of pH within the renal tubules.

Suitable Lifestyle for People with Renal Tubular Dysgenesis

Suitable lifestyle options for people with Renal tubular dysgenesis include the following:

1. Maintain healthy living habits, such as regular work and rest, ensure adequate sleep, and avoid bad habits such as smoking and drinking;

2. Increase moderate exercise, such as walking , jogging, swimming, etc. , can help promote blood circulation and reduce the burden on the kidneys;

3. Pay attention to your diet, maintain a balanced nutrition, and eat more vegetables, fruits, whole grains and other foods rich in vitamins, minerals and dietary fiber;

4. Stay in good health Mentality, avoid overwork, excessive stress, etc. , which is conducive to recovery;

5. Check kidney function regularly, follow the doctor's advice, and adjust the treatment plan in a timely manner. In short, people suffering from Renal tubular dysgenesis should focus on maintaining physical and mental health, actively cooperate with treatment, and follow the doctor's living habits and recommendations.

Other Diseases

Renal Tubular AcidosisThyroid DysgenesisReticular DysgenesisAnterior Segment DysgenesisRenal FailureRenal Hypomagnesemia 3Renal HypouricemiaRenal HypertensionRenal OncocytomaRenal DysplasiaRenal Medullary CarcinomaMulticystic Renal DysplasiaRenal-Hepatic-Pancreatic DysplasiaRenpenning SyndromeRestless Legs SyndromeRestrictive DermopathyRetinal ColobomaRetinal DegenerationRetinal DetachmentRetinal Diseases