About Primary Nephrotic Syndrome

Primary Nephrotic Syndrome, also known as minimal change disease, is a rare kidney disease that affects the kidneys in the early stages of life. It is characterized by the loss of a small number of nephrons, which are the basic units of the kidney responsible for filtering waste products from the blood. The condition is usually detected in childhood or early adulthood, and it can progress to more severe forms of the disease, leading to kidney failure or other serious health complications. The exact cause of Primary Nephrotic Syndrome is not known, but it is thought to be related to a genetic or environmental factor. The most common symptom is the appearance of small, white nodules on the kidneys, which can be felt by the healthcare provider. The disease can also cause symptoms such as passing large amounts of urine, proteinuria, or edema. Primary Nephrotic Syndrome is treated with a combination of medications, dietary changes, and kidney transplantation in severe cases. It is important to seek medical attention early on to receive proper diagnosis and treatment. With proper care, many people with Primary Nephrotic Syndrome can lead happy and fulfilling lives.

Major Symptoms of Primary Nephrotic Syndrome

The main symptoms of Primary Nephrotic Syndrome include:

1. Massive proteinuria: The amount of protein excretion in the patient's urine increases significantly, exceeding the clearance capacity of the glomerular filtration membrane, leading to proteinuria.

2. Hypoalbuminemia: The level of plasma protein decreases, resulting in a decrease in plasma colloid osmotic pressure, and water enters the tissue space from the blood vessels, causing edema.

3. Hyperlipidemia: Increased plasma lipid levels, mainly manifested as total cholesterol, triglycerides and other dyslipidemia.

4. Edema: Large amounts of proteinuria lead to loss of plasma protein, reduction of plasma colloid osmotic pressure, and water entering the interstitial space from blood vessels, causing edema.

5. Hypertension: Large amounts of proteinuria cause blood volume to decrease, resulting in a decrease in glomerular effective filtration pressure, thus causing hypertension.

6. Abnormal renal function: Due to damage to the glomerular filtration membrane, glomerular filtration function decreases, causing abnormal renal function.

7. Hematuria: Some patients will have hematuria, mostly microscopic hematuria, and a few patients may have gross hematuria.

8. Nervous system symptoms: Some patients may develop neurological symptoms, such as fatigue, headache, difficulty concentrating, etc.

9. Digestive system symptoms: Some patients may develop digestive system symptoms, such as nausea, vomiting, diarrhea, etc.

10. Other symptoms: Patients may also experience other symptoms, such as palpitations, shortness of breath, anxiety, etc.

Suitable Lifestyle for People with Primary Nephrotic Syndrome

Patients suffering from Primary Nephrotic Syndrome should adopt a special lifestyle. This lifestyle includes:

1. Regular work and rest time: Patients should get up, go to bed, eat, etc. at fixed times every day to maintain normal body functions.

2. Reasonable diet: Patients should follow the advice of doctors or nutritionists and eat low-salt, low-fat, low-sugar foods, and eat more foods rich in protein, vitamins and minerals to help the body recover.

3. Appropriate exercise: Patients should do appropriate exercise according to the doctor's advice, such as walking, jogging, etc. , to promote blood circulation and enhance the body's immunity.

4. Maintain a good attitude: Patients should maintain a positive and optimistic attitude and communicate with family and friends to relieve stress and anxiety.

5. Comply with medical advice: Patients should abide by the doctor's treatment plan, take medications on time, and undergo regular check-ups to ensure the effectiveness and safety of treatment.

Other Diseases

Nephrotic Syndrome Congenital Nephrotic Syndrome Nephrotic Syndrome Type 1 Primary Bone Primary Hyperparathyroidism Primary Aldosteronism Primary Macroglobulinemia Primary Erythromelalgia Primary Hyperoxaluria Primary Secondary Nephritis

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