About Diffuse Scleroderma

Diffuse Scleroderma, also known as diffuse systemic sclerosis, is related to scleroderma, familial progressive and crest syndrome, and has symptoms including exanthema, pruritus and hidebound skin. An important gene associated with Diffuse Scleroderma is TOP1 (DNA Topoisomerase I), and among its related pathways/superpathways is Angiotensin II receptor type 1 pathway. The drugs Ambrisentan and Bosentan have been mentioned in the context of this disorder. Affiliated tissues include lung, skin and endothelial.

Major Symptoms of Diffuse Scleroderma

Scleroderma is a chronic autoimmune disorder characterized by the thickening and scarring of skin and connective tissue. Some major symptoms include joint pain and stiffness, skin rashes and lesions, and fatigue. The exact cause of Scleroderma is not known, but it is thought to involve an overactive immune system that targets the skin and connective tissue. Treatment typically involves a combination of medications, physical therapy, and dietary changes.

Suitable Lifestyle for People with Diffuse Scleroderma

Suitable lifestyle options for people with Diffuse Scleroderma include:

1. Maintain a healthy lifestyle: maintain adequate sleep time, eat a balanced diet, exercise appropriately, and avoid bad habits such as smoking and drinking.

2. Maintain a good mental state: avoid negative emotions such as anxiety and depression, learn to relieve stress, and seek psychological support.

3. Avoid direct skin contact with irritants: avoid using substances that may cause skin inflammation, such as detergents, soaps, etc.

4. Keep your skin moist: Use a moisturizer to keep your skin moisturized, but avoid using moisturizers that contain alcohol.

5. Avoid high temperature: Avoid high temperature and chemical substances that irritate the skin, and pay attention to the stimulation of sunlight and hot water.

6. Maintain a regular schedule: Maintain a regular schedule to avoid staying up late and being overtired.

7. Seek professional medical help: People suffering from Diffuse Scleroderma should seek professional medical help as early as possible and treat and manage it according to the doctor's recommendations.

Other Diseases

SclerodermaLocalized SclerodermaDiffuse Palmoplantar KeratodermaDiffuse Mesangial SclerosisDiffuse Intrinsic Pontine GliomaDiffuse Idiopathic Pulmonary Neuroendocrine Cell HyperplasiaDiGeorge SyndromeDiscoid Lupus ErythematosusDisseminated Intravascular CoagulationDisseminated Superficial Actinic PorokeratosisDistal MyopathyDistal Myopathy 2Distal Spinal Muscular AtrophyDiverticulitisDNA Ligase IV DeficiencyDOCK8 Immunodeficiency SyndromeDominant Optic AtrophyDonnai-Barrow SyndromeDouble Outlet Right VentricleDowling-Degos Disease