About Diffuse Palmoplantar Keratoderma

Diffuse Palmoplantar Keratoderma, also known as diffuse palmoplantar hyperkeratosis, is related to palmoplantar keratoderma, nonepidermolytic and naxos disease. An important gene associated with Diffuse Palmoplantar Keratoderma is DSG1 (Desmoglein 1), and among its related pathways/superpathways are Keratinization and RND3 GTPase cycle. Affiliated tissues include skin, heart and lung, and related phenotype is integument.

Major Symptoms of Diffuse Palmoplantar Keratoderma

Diffuse palmoplantar keratoderma (DMPK) is a skin condition characterized by the appearance of large, raised patches on the soles of the feet and hands. The major symptoms include:

1. Itchy, burning, and tender patches on the soles of the feet and hands

2. A red, scaly appearance on the skin

3. Increased risk of developing skin infections, such as fungal infections

4. Difficulty with shoes and socks

5. Pain and discomfort in the affected areas

6. A persistent, itchy rash that tends to be dry and itchy

7. A tendency to bleed or cause skin infectionsThese symptoms can vary in severity and frequency, and individuals with DMPK may experience other symptoms that are specific to their condition. Treatment typically involves managing symptoms with medicated shampoos, creams, or injections, as well as using protective gear such as gloves and socks to prevent skin infections. In severe cases, surgery may be necessary.

Suitable Lifestyle for People with Diffuse Palmoplantar Keratoderma

People with Diffuse palmoplantar keratoderma (keratodermatitis of the palms and soles) should avoid excessively dry environments, avoid using harsh cosmetics and cleansers, keep their skin moist, and avoid wearing synthetic or rough shoes, especially those with poor breathability. shoe. It is recommended to wear cotton, breathable shoes and clothing and avoid prolonged exposure to the sun or cold conditions. In addition, maintaining a healthy lifestyle, such as regular diet, adequate sleep and appropriate exercise, can help improve skin condition. If you have keratodermatitis of the palms and soles of the feet, consult a dermatologist for more specific advice.

Other Diseases

Palmoplantar KeratodermaEpidermolytic Palmoplantar KeratodermaNon-Epidermolytic Palmoplantar KeratodermaDiffuse SclerodermaDiffuse Mesangial SclerosisDiffuse Intrinsic Pontine GliomaDiffuse Idiopathic Pulmonary Neuroendocrine Cell HyperplasiaDiGeorge SyndromeDiscoid Lupus ErythematosusDisseminated Intravascular CoagulationDisseminated Superficial Actinic PorokeratosisDistal MyopathyDistal Myopathy 2Distal Spinal Muscular AtrophyDiverticulitisDNA Ligase IV DeficiencyDOCK8 Immunodeficiency SyndromeDominant Optic AtrophyDonnai-Barrow SyndromeDouble Outlet Right Ventricle