About Malonyl-CoA Decarboxylase Deficiency

Malonyl-Coa Decarboxylase Deficiency, also known as malonic aciduria, is related to atrial standstill 1 and inherited metabolic disorder, and has symptoms including abdominal pain, diarrhea and seizures. An important gene associated with Malonyl-Coa Decarboxylase Deficiency is MLYCD (Malonyl-CoA Decarboxylase). Affiliated tissues include heart, brain and liver, and related phenotypes are pachygyria and intellectual disability

Major Symptoms of Malonyl-CoA Decarboxylase Deficiency

Malonyl-CoA decarboxylase (MCD) deficiency is a rare metabolic disease. The main symptoms include:

1. Obesity: MCD deficiency leads to fat metabolism disorder, making the patient unable to consume body fat normally, leading to obesity.

2. Ketosis: Because fat cannot be consumed normally, patients with MCD deficiency will experience ketosis, which is manifested by symptoms such as shortness of breath, nausea, vomiting, and increased heart rate.

3. Neuropsychiatric symptoms: MCD deficiency can lead to neuropsychiatric symptoms, including cognitive impairment, behavioral abnormalities, schizophrenia, etc.

4. Digestive system symptoms: MCD deficiency will affect the normal operation of the digestive system, and patients may experience symptoms such as diarrhea, constipation, nausea, and vomiting.

5. Skin symptoms: MCD deficiency can cause skin symptoms, including dry skin, itching, inflammation, etc.

6. Other symptoms: MCD deficiency may also cause other symptoms, such as difficulty breathing, irregular heartbeat, high blood pressure, etc.

Suitable Lifestyle for People with Malonyl-CoA Decarboxylase Deficiency

Malonyl-CoA decarboxylase deficiency, a disease caused by a lack of coenzyme A, often causes pain, muscle stiffness, and joint pain. Therefore, patients with this disease need to pay special attention to their daily habits to reduce symptoms and delay disease progression. First, patients need to avoid standing or sitting for long periods of time, as this may worsen pain and stiffness. Instead, engage in exercises such as walking, short jogging, yoga, and swimming to reduce muscle tension and stiffness. Second, patients need to avoid foods high in fat and sugar, as these may worsen symptoms. Instead, increase your intake of healthy foods like vegetables, fruits, whole grains, and protein to provide your body with the nutrients it needs. In addition, patients also need to pay attention to pain management in daily life. Over-the-counter medications are available to relieve pain, but should be used as recommended by your doctor. During pain, patients can use hot compresses, cold compresses, massage and other methods to reduce pain and relieve muscle stiffness. Finally, patients need regular rehabilitation exercises and massage to help restore muscle function and relieve pain. These activities can be performed under the guidance of a physical therapist to help patients better restore physical function. In summary, patients with Malonyl-CoA decarboxylase deficiency need to pay special attention to their daily lifestyle habits to reduce symptoms and delay disease progression. Patients can work with their doctors and physical therapists to develop a treatment plan that works for them individually.

Other Diseases

Pyruvate Decarboxylase Deficiency Creatine Deficiency Syndrome due to AGAT Deficiency IgA Deficiency Coenzyme Q10 Deficiency Antithrombin III Deficiency Vitamin K Deficiency 5-Oxoprolinase Deficiency HIBCH Deficiency Transcobalamin Deficiency NGLY1 Deficiency

Related Products