About Progressive External Ophthalmoplegia

Chronic Progressive External Ophthalmoplegia, also known as progressive external ophthalmoplegia, is related to progressive external ophthalmoplegia with mitochondrial dna deletions, autosomal dominant 1 and progressive external ophthalmoplegia with mitochondrial dna deletions, autosomal dominant 4, and has symptoms including ophthalmoplegia An important gene associated with Chronic Progressive External Ophthalmoplegia is TWNK (Twinkle MtDNA Helicase), and among its related pathways/superpathways are Metabolism and Organelle biogenesis and maintenance. The drugs 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid and Protective Agents have been mentioned in the context of this disorder. Affiliated tissues include eye, skeletal muscle and heart, and related phenotypes are Strongly decreased CFP-tsO45G cell surface transport and Strongly decreased CFP-tsO45G cell surface transport

Major Symptoms of Progressive External Ophthalmoplegia

Progressive external ophthalmoplegia (PE) is a rare progressive eye condition characterized by a progressive decline in vision and photoreceptor function. The major symptoms include progressive loss of visual acuity, photoreceptor loss, and clumsy or dexterous eye movements. The symptoms usually appear in early childhood and may gradually worsen, leading to blindness. Treatment methods include medication, surgery, and visual training.

Suitable Lifestyle for People with Progressive External Ophthalmoplegia

People with Progressive external ophthalmoplegia (PEO) usually need to pay special attention to their eye health and lifestyle. The disease causes muscle weakness that affects eye movement and daily activities, so patients need to develop an appropriate lifestyle routine to cope with this challenge.

1. Maintain a regular schedule: Go to bed and wake up at the same time every day to ensure adequate sleep and avoid staying up late.

2. Maintain good living habits: quit smoking and limit alcohol consumption, and try to avoid using electronic products for long periods of time to reduce the burden on eye muscles.

3. Balanced nutrition: Eat more foods rich in vitamin C, vitamin E, zinc, calcium and other foods that are good for your eyes, such as fruits, vegetables, fish, nuts and protein.

4. Exercise: Moderate physical exercise can improve the vitality of eye muscles and relieve symptoms. However, strenuous exercise should be avoided to avoid further damage to the eyes.

5. Stay in a good mood: Maintain good communication with family and friends, share your illness and feelings, and avoid feeling depressed.

6. Comply with the doctor's advice: Under the guidance of the doctor, use the medicine in accordance with the drug instructions and the doctor's advice, and review regularly to ensure that the condition is effectively controlled.

7. Learn some simple life skills: Learn some basic daily skills, such as cooking, laundry, tidying up the room, etc. , so that you can complete them independently in daily life.

8. Seek psychological support: Maintain communication with family, friends or a psychologist, and seek psychological support to cope with the psychological pressure caused by the disease. In short, people with Progressive external ophthalmoplegia need to relieve symptoms through a regular lifestyle and actively cope with the challenges brought by the disease. At the same time, patients, family and friends should pay close attention to changes in eye symptoms, seek medical treatment promptly, and follow the doctor's treatment recommendations.

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