About Hypermethioninemia

Glycine N-Methyltransferase Deficiency, also known as gnmt deficiency, is related to hypermethioninemia and methionine adenosyltransferase i/iii deficiency. An important gene associated with Glycine N-Methyltransferase Deficiency is GNMT (Glycine N-Methyltransferase), and among its related pathways/superpathways are Metabolism and Regulation of expression of SLITs and ROBOs. Affiliated tissues include liver, brain and nk cells, and related phenotypes are hepatomegaly and elevated hepatic transaminase

Major Symptoms of Hypermethioninemia

Hypermethioninemia is a rare form of hyperthyroidism. Its main symptoms include:

1. Accelerated metabolic rate: The patient's thyroxine level continues to increase, resulting in accelerated metabolic rate, manifested by palpitations, hand tremors, excessive sweating, and weight loss. Decline etc.

2. Eye problems: Patients may experience symptoms such as eye dryness, stinging, vision loss, etc. , and may even develop hyperthyroid eye disease.

3. Skin problems: The skin is prone to symptoms such as itching, dryness, and peeling. In severe cases, it may be accompanied by hyperthyroidism dermatitis.

4. Oral problems: Oral problems such as oral ulcers and gingivitis are relatively common.

5. Weight changes: Patients may experience symptoms such as weight loss and weight loss, but hyperthyroidism itself does not affect weight.

6. Mental state: Patients may have psychological problems such as inattention, anxiety, and depression, and may even develop hyperthyroidism.

7. Reproductive system problems: Female patients may experience symptoms such as reduced menstruation and infertility, while male patients may experience sexual dysfunction.

8. Cardiovascular system problems: Patients may experience symptoms such as palpitations and shortness of breath, which may lead to hyperthyroid heart disease in severe cases.

9. Nervous system problems: Patients may suffer from headaches, insomnia, convulsions and other symptoms, and may even cause hyperthyroid epilepsy.

10. Digestive system problems: Patients may experience symptoms such as diarrhea and constipation. It should be noted that Hypermethioninemia is a severe form of hyperthyroidism, and patients need prompt medical treatment to avoid more serious complications.

Suitable Lifestyle for People with Hypermethioninemia

Hypermethioninemia is an inherited metabolic disease characterized by excessive levels of methionine in the liver. Suitable lifestyle options for people with Hypermethioninemia include:

1. Healthy diet: limit the intake of methionine and avoid foods high in methionine, such as eggs, milk, meat, fish and beans.

2. Medication: Depending on the condition and the doctor's advice, you may need to take medications, such as liver medications, nutritional supplements, and vitamins.

3. Exercise: Moderate aerobic exercise can increase the body's metabolic rate and reduce symptoms.

4. Control your weight: Maintaining a healthy weight can reduce the burden on your liver and reduce symptoms.

5. Avoid drinking alcohol and smoking: Drinking alcohol and smoking will increase the burden on the liver and aggravate symptoms.

6. Regular examination: Regularly check the condition and the effect of drug treatment, and adjust lifestyle and treatment plan in a timely manner. Please note that these recommendations are for guidance only and specific recommendations should be based on individual circumstances and your doctor's advice.

Other Diseases

Related Products