About Hypercalcemia

Hypercalcemia, Infantile, 1, also known as infantile hypercalcemia, is related to idiopathic infantile hypercalcemia and hypocalciuric hypercalcemia, familial, type i. An important gene associated with Hypercalcemia, Infantile, 1 is CYP24A1 (Cytochrome P450 Family 24 Subfamily A Member 1), and among its related pathways/superpathways are GPCR downstream signalling and Class A/1 (Rhodopsin-like receptors). The drugs Salmon calcitonin and Cholecalciferol have been mentioned in the context of this disorder. Affiliated tissues include bone, kidney and heart, and related phenotypes are nephrolithiasis and intellectual disability

Major Symptoms of Hypercalcemia

The main symptoms of hypercalcemia include:

1. Tetany: muscle spasms in the hands and feet, which may lead to muscle pain and joint stiffness.

2. Nausea and vomiting: Due to excessive calcium ion concentration in the blood, nausea, vomiting and diarrhea may occur.

3. Constipation: Hypercalcemia may cause intestinal motility to slow down, leading to constipation.

4. Dyspnea: Hypercalcemia may cause paralysis of respiratory muscles, causing difficulty in breathing.

5. Fatigue and weakness: Hypercalcemia may affect the body's energy levels, causing fatigue and weakness.

6. Muscle Weakness: Hypercalcemia may lead to decreased muscle strength and endurance.

7. Bone pain: Hypercalcemia may lead to an increase in bone density, causing bone pain.

8. Numbness of hands and feet: The nerve endings of hands and feet are stimulated, which may lead to numbness of hands and feet.

Suitable Lifestyle for People with Hypercalcemia

People with Hypercalcemia need to pay special attention to their diet and lifestyle to avoid any adverse effects. The following are some lifestyle options suitable for people with Hypercalcemia:

1. Diet: Limit the intake of foods and beverages containing caffeine and calcium such as coffee, tea, carbonated drinks, and milk. The diet should include adequate amounts of vitamin D and calcium, such as fish, meat, legumes, nuts, and vitamin supplements.

2. Exercise: Moderate aerobic exercise can help lower blood pressure and cholesterol, reduce bone pain and the risk of fractures. But high-intensity exercise, such as running and weightlifting, should be avoided.

3. Sleep: Ensure adequate sleep time to help the body maintain normal calcium levels.

4. Avoid stimulating substances: Avoid caffeine and certain stimulating drugs, such as codeine and nicotine.

5. Regular examinations: Get regular examinations to ensure that blood calcium levels are within the normal range, and follow your doctor's recommendations for treatment. Hypercalcemia patients should follow the doctor's treatment recommendations and pay attention to adjustments in diet and lifestyle to maintain bone health.

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