About 3-Methylglutaconic Aciduria Type I

3-Methylglutaconic Aciduria, Type I, also known as 3-methylglutaconyl-coa hydratase deficiency, is related to 3-methylglutaconic aciduria, type iv and 3-methylglutaconic aciduria, and has symptoms including athetosis and cerebellar ataxia. An important gene associated with 3-Methylglutaconic Aciduria, Type I is AUH (AU RNA Binding Methylglutaconyl-CoA Hydratase). Affiliated tissues include brain, skeletal muscle and placenta, and related phenotypes are failure to thrive and 3-methylglutaconic aciduria

Major Symptoms of 3-Methylglutaconic Aciduria Type I

3-Methylglutaconic aciduria type I, also known as severity subtype, is an inherited metabolic disease. The main symptoms include:

1. Abdominal pain and diarrhea: Patients may experience abdominal pain and diarrhea, especially after eating.

2. Vomiting: Patients may vomit, especially after eating or while sleeping.

3. Constipation: Patients may experience constipation, making it difficult to pass stool.

4. Glucose in urine and stool: Patients may detect glucose in their urine and stool, which may be due to the body's inability to process sugar properly.

5. Fatigue and loss of appetite: Patients may feel tired and have a loss of appetite, especially after eating.

6. Anemia: Patients may experience symptoms of anemia, such as fatigue and lack of concentration.

7. Immune system problems: Patients may develop immune system problems, leading to symptoms such as susceptibility to infections, fever, and joint pain. It is important to note that these symptoms may not apply to all patients and may vary from individual to individual. If you have these symptoms, it is recommended that you seek medical treatment promptly and receive diagnosis and treatment from a professional doctor.

Suitable Lifestyle for People with 3-Methylglutaconic Aciduria Type I

3-methylglutaconic aciduria (MGAA) is an inherited metabolic disease in which the patient's liver cannot properly metabolize 3-methylglutaconic acid (an amino acid), causing it to accumulate and cause various health problems. For patients with MGAA, lifestyle modifications are important to help reduce symptoms and slow disease progression. For patients with MGAA, the following lifestyle is applicable:

1. Dietary adjustment: avoid high-protein and high-fat foods, increase carbohydrate intake, and maintain adequate vitamins and minerals. It is recommended that the diet include adequate vegetables, fruits, whole grains, legumes, and low-fat protein sources.

2. Control drinking and caffeine: These substances can stimulate the liver to produce more 3-methylglutaconic acid, so drinking and caffeine intake should be avoided or limited as much as possible.

3. Supplement vitamins and minerals: Since MGAA patients may have problems with the absorption and utilization of vitamins and minerals, it is recommended to supplement relevant nutrients, such as vitamins B, C, D, E, K, as well as calcium, iron and other minerals.

4. Maintain a good routine and sleep: Maintaining a regular routine and sleep can help reduce symptoms, relieve fatigue, and help the liver metabolize and remove 3-methylglutaconic acid.

5. Carry out appropriate exercise: Proper exercise can increase the body's metabolic rate, help reduce symptoms, and enhance the body's resistance.

6. Regular examinations: Conduct regular examinations to ensure that the patient's condition is under control and monitor changes in symptoms at any time. In short, lifestyle adjustments are very important for MGAA patients. By adjusting diet, controlling alcohol consumption and caffeine, supplementing nutrients, maintaining a good routine and sleep, performing appropriate exercise, and regular examinations, we can help patients reduce symptoms, delay disease progression, and improve quality of life.

Other Diseases

3-Methylglutaconic Aciduria Type IV 3-Methylglutaconic Aciduria Glutaric Aciduria Type 3 Glutaric Aciduria Type 2 Glutaric Aciduria Type 1 CblC Type Methylmalonic Aciduria and Homocystinuria Orotic Aciduria D-2-Hydroxyglutaric Aciduria L-2-Hydroxyglutaric Aciduria 3-Hydroxy-3-Methylglutaric Aciduria

Related Products