About D-2-Hydroxyglutaric Aciduria

D-2-Hydroxyglutaric Aciduria 1, also known as d-2-hydroxyglutaric aciduria, is related to d-2-hydroxyglutaric aciduria 2 and combined d-2- and l-2-hydroxyglutaric aciduria, and has symptoms including dyspnea, seizures and stridor. An important gene associated with D-2-Hydroxyglutaric Aciduria 1 is D2HGDH (D-2-Hydroxyglutarate Dehydrogenase), and among its related pathways/superpathways are Metabolism and "Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. ". Affiliated tissues include brain, skeletal muscle and cortex, and related phenotypes are macrocephaly and intellectual disability

Major Symptoms of D-2-Hydroxyglutaric Aciduria

D-2-Hydroxyglutaric aciduria (DHG) is a rare genetic disorder characterized by the accumulation of high levels of 2-hydroxyglutaric acid (2-HGA) in the blood and urine. The major symptoms include progressive muscle weakness and wasting, shortness of breath, and joint pain. Additionally, individuals with DHG may experience cognitive impairment, including memory and learning difficulties. The disease is usually diagnosed in adulthood, and there is currently no cure. Treatment is focused on managing symptoms and improving quality of life.

Suitable Lifestyle for People with D-2-Hydroxyglutaric Aciduria

First, we need to understand the characteristics of the disease D-2-Hydroxyglutaric aciduria. It is an inherited metabolic disorder in which the body's levels of certain amino acids are abnormally elevated, including D-2-Hydroxyglutaric aciduria. The disease often leads to serious health problems such as abnormal liver function, kidney damage, and neurological problems. Based on this information, we can deduce that lifestyle modifications are very important for patients with D-2-Hydroxyglutaric aciduria. These patients need to follow their doctor's advice and improve their lifestyle as much as possible to reduce the damage the disease does to their bodies. Specifically, patients need to avoid unhealthy lifestyles such as drinking, overeating, and high-sugar and high-fat diets. At the same time, they need to maintain a good work and rest routine, exercise regularly, and maintain a good mental state. In addition, patients need to actively receive treatment and follow the doctor's medication instructions. In short, for patients suffering from D-2-Hydroxyglutaric aciduria, lifestyle adjustments are very important. They need to follow the doctor's recommendations and improve their lifestyle as much as possible to reduce the damage of the disease to the body.

Other Diseases

L-2-Hydroxyglutaric Aciduria Orotic Aciduria 3-Methylglutaconic Aciduria Glutaric Aciduria Type 3 3-Methylglutaconic Aciduria Type IV Glutaric Aciduria Type 1 3-Methylglutaconic Aciduria Type I Glutaric Aciduria Type 2 3-Hydroxy-3-Methylglutaric Aciduria CblC Type Methylmalonic Aciduria and Homocystinuria

Related Products