About Progressive Familial Intrahepatic Cholestasis Type 3

Cholestasis, Progressive Familial Intrahepatic, 3, also known as pfic3, is related to familial intrahepatic cholestasis and cholangitis, and has symptoms including diarrhea, icterus and pruritus. An important gene associated with Cholestasis, Progressive Familial Intrahepatic, 3 is ABCB4 (ATP Binding Cassette Subfamily B Member 4), and among its related pathways/superpathways are Metabolism and Transport of inorganic cations/anions and amino acids/oligopeptides. Affiliated tissues include liver and spleen, and related phenotypes are splenomegaly and hepatomegaly

Major Symptoms of Progressive Familial Intrahepatic Cholestasis Type 3

Progressive familial intrahepatic cholestasis type 3 (PFIC-3), also known as nonalcoholic steatohepatitis (NASH), is a progressive autoimmune liver disease that primarily affects children. The major symptoms of PFIC-3 include persistent jaundice, itching, and fatigue. Other symptoms may include abdominal pain and discomfort, loss of appetite, and a weak immune system.

Suitable Lifestyle for People with Progressive Familial Intrahepatic Cholestasis Type 3

The suitable lifestyle for people with Progressive familial intrahepatic cholestasis type 3 includes the following points:

1. Healthy diet: This disease is closely related to diet. Patients should follow the dietary principles of low fat, low cholesterol, low sugar, and high fiber. Eat vegetables, fruits, whole grains and foods rich in healthy fats.

2. Moderate exercise: Exercise can help relieve symptoms, increase the patency of intrahepatic bile ducts, and reduce the accumulation of bile in the liver. Patients can choose appropriate exercise methods, such as walking, jogging, swimming, etc.

3. Quit smoking and limit alcohol consumption: Both smoking and drinking may increase the burden on the liver and induce or aggravate the symptoms of Progressive familial intrahepatic cholestasis type 3. Patients should try to quit smoking and limit drinking, or avoid smoking and excessive drinking.

4. Control weight: Obesity increases the risk of this disease. Patients should maintain a healthy weight and avoid overeating and excessive drinking.

5. Regular check-ups: Patients should go to the hospital for regular check-ups to ensure that the disease is treated in a timely manner.

6. Maintain a good attitude: A positive attitude can help enhance the body's immunity, reduce symptoms, and prevent complications.

7. Follow the doctor's treatment recommendations: Under the guidance of the doctor, patients should take medications on time and follow the doctor's diet and exercise recommendations to better restore health.

Other Diseases

Progressive Familial Intrahepatic Cholestasis Type 2 Progressive Familial Intrahepatic Cholestasis Type 1 Progressive Familial Intrahepatic Cholestasis Intrahepatic Cholestasis Benign Recurrent Intrahepatic Cholestasis 1 Gaze Palsy, Familial Horizontal, with Progressive Scoliosis, 2 Cholestasis Intrahepatic Cholecystolithiasis Progressive Myoclonic Epilepsy Progressive Multifocal Leukoencephalopathy

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